WebObjective: Lysine-specific demethylase 2A (KDM2A), a specific H3K36me1/2 demethylase, has been reported to be closely associated with several types of cancer. … WebThe histone demethylase, lysine (K)-specific demethylase 2A (KDM2A), and the mammalian paralog, lysine (K)-specific demethylase 2B (KDM2B), are evolutionarily conserved and ubiquitously expressed members of the JmjC-domain-containing histone demethylase family. A previous study determined that KDM2A and KDM2B can regulate …
Lysine-specific demethylase 2A enhances binding of …
Web4 apr. 2024 · Chemotherapy, targeted therapy, and immunotherapy are effective against most tumors, but drug resistance remains a barrier to successful treatment. Lysine-specific demethylase 1 (LSD1), a member of histone demethylation modifications, can regulate invasion, metastasis, apoptosis, and immune escape of tumor cells, which are … Web9 oct. 2024 · The methylation status of histones plays a crucial role in many cellular processes, including follicular and oocyte development. Lysine-specific demethylase … myron butler my tribute
Depletion of histone demethylase KDM2A inhibited cell ... - PubMed
Web14 ian. 2011 · NX_Q9Y2K7 - KDM2A - Lysine-specific demethylase 2A - Function. Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. May also … Web27 dec. 2024 · lysine-specific demethylase 2A, F-box and leucine-rich repeat protein 11, F-box protein containing leucine repeats, F-box/LRR-repeat protein 11, [Histone-H3] … Weblysine (K)-specific demethylase 2A. Synonyms. 5530401A10Rik, Cxxc8, Fbl7, Fbxl11, Gm4560, Jhdm1a, lalina Feature Type. protein coding gene. IDs. MGI ... J:330905 Xiong X, et al., Oocyte-Specific Knockout of Histone Lysine Demethylase KDM2a Compromises Fertility by Blocking the Development of Follicles and Oocytes. Int J Mol Sci. 2024 Oct … the song blu ray